Abstract Enhanced expression of anti-apoptotic B-cell lymphoma 2 (BCL-2) protein is frequent in cancer.Targeting of BCL-2 with the specific inhibitor ABT-199 (Venetoclax) has significant clinical activity in malignant diseases such as chronic lymphocytic leukemia and multiple myeloma.The small molecule drug ABT-199 mimics the pro-apoptotic BCL-2 ho

Abstract Some snakes emit hissing calls which are imitated edgewater shoes by birds to deter potential predators.However, the effect of these snake and bird hisses on anuran risk recognition is not yet explored.Here we hypothesize that these hisses may advertise dangers to frogs and evoke their anti-predator responses.We used little torrent frogs (

BackgroundIntravenous lipid emulsion has been used to treat systemic toxicity of local anesthetics.The goals of this chocolate chip cookie purse in vitro study were to determine the ability of two lipid emulsions (Intralipid® and Lipofundin® MCT/LCT) to reverse toxic dose local anesthetic-induced vasodilation in isolated rat aortas.MethodsIsolate

The increasing number of foreigners entered Iran, especially the Europeans in the 19th Century A.D.enabled them to know more about the Iranian society.Moreover, the writers of Foreign travelers who got interested in the social and cultural issues of Iran about which recorded important information.For example, the Kurds, one of the ancient Iranian t

For most people, playing video games is a normal recreational activity, cyspera cream where to buy with little disruption to gamers’ emotional, social, or physical health and well-being.However, for a small percentage of gamers, video gaming can become pathological (Fam, 2018).Substantial research has examined pathological gaming in teens and you